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10X Genomics visium spatial gene expression analysis
Visium Spatial Gene Expression Analysis, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/visium+spatial+gene+expression+analysis/expression+gene+slides+spatial+visium/pmc12703572-40-5-3
Average 86 stars, based on 1 article reviews
visium spatial gene expression analysis - by Bioz Stars, 2026-09
86/100 stars

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Gene Expression:

Article Title: Spatial Single-cell Analysis Decodes Cortical Layer and Area Specification
Article Snippet: .. Visium Spatial Gene Expression Analysis (10x Genomics) was performed according to manufacturer’s user guide and demonstrated protocol (Visium CytAssist Spatial Gene Expression for Fresh Frozen – Methanol Fixation, H&E Staining, Imaging & Destaining, CG000614, Rev A; Visium CytAssist Spatial Gene Expression Reagent Kits User Guide, CG000495, Rev D). ..

Article Title: Spatial transcriptomics of a giant pilomatricoma.
Article Snippet: .. Giant PMs are a rare World Health Organization (WHO)-acknowledged PM variant that is greater than 4 cm in size, frequently ulcerate and are more likely to simulate a malignant neoplasm on clinical exam.4 Most PMs harbor mutations in the CTNNB1 gene5 leading to constitutive beta-catenin/lymphoid enhancer binding factor (LEF) target gene activation to control proliferation, differentiation, and survival.6,7 Simultaneous gain of chromosome 18 harboring the BCL2 apoptosis regulator (BCL2) gene is also a recurrent abnormality accompanied by BCL2 protein overexpression.8,9 Finally, one study has shown a positive correlation between yes-associated protein (YAP) expression and PM size.10 Spatial gene expression analyses allow for the measurement of gene expression while retaining spatial information, enabling visualization and statistical comparisons of gene expression differences across tissue regions.11,12 Here, we report 10X Genomics Visium Spatial Gene Expression analysis of a giant PM. ..

Article Title: Spatial transcriptomics of a giant pilomatricoma.
Article Snippet: .. See the T erm s and C onditions (https://onlinelibrary.w iley.com /term s-and-conditions) on W iley O nline L ibrary for rules of use; O A articles are governed by the applicable C reative C om m ons L icense As part of a larger institutional review board-approved study, we subjected a representative region of the patient's giant PM (Figure 2A) to 10X Genomics Visium Spatial Gene Expression analysis using the Space Ranger v1.3.1 data pipeline.12 We visualized and analyzed the resulting data in the 10X Genomics Loupe Browser v6.0.0 and applied t-distributed stochastic neighbor embedding (t-SNE)13,14 which revealed five statistically distinct transcriptomic clusters (Figure 2B,C), one of which (Cluster 5) constituted benign Cluster 1 Cluster 2 Cluster 3 Cluster 4 Cluster 5 Stroma Basal Layer Keratin (A) (B) (C) (D) F IGURE 2 Localization of unique gene expression clusters within giant pilomatricoma. (A) Image of region selected for spatial gene expression profiling. ..

Article Title: Magnifying Glass on Sinonasal NUT Carcinoma Heterogeneity via Spatial Transcriptomics
Article Snippet: Spatial transcriptomics (ST) sequencing is one such methodology that offers a unique approach to elucidate cancer cell heterogeneity and spatial distributions within tissues by linking gene expression with spatial location on tissue sections [ , , ]. .. Here, we report 10X Genomics Visium spatial gene expression analysis in a consecutive series of NC. ..

Article Title: Spatial transcriptomics reveals human cortical layer and area specification.
Article Snippet: Visium spatial transcriptomic analysis Visium spatial gene expression analysis (10x Genomics) was performed according to the manufacturer’s user guide and demonstrated protocol (‘Visium CytAssist Spatial Gene Expression for Fresh Frozen–Methanol Fixation, H&E Staining, Imaging & Destaining, CG000614, Rev A; Visium CytAssist Spatial Gene Expression Reagent Kits User Guide, CG000495, Rev D’). .. Visium spatial transcriptomic analysis Visium spatial gene expression analysis (10x Genomics) was performed according to the manufacturer’s user guide and demonstrated protocol (‘Visium CytAssist Spatial Gene Expression for Fresh Frozen–Methanol Fixation, H&E Staining, Imaging & Destaining, CG000614, Rev A; Visium CytAssist Spatial Gene Expression Reagent Kits User Guide, CG000495, Rev D’). ..

Article Title: Muscle spatial transcriptomic reveals heterogeneous profiles in untreated juvenile dermatomyositis and the persistence of pathological signature after remission
Article Snippet: .. To define the transcriptomic signature of the different areas of affected muscle in JDM, we performed 10X Genomics Visium Spatial Gene Expression analysis on the muscle obtained at diagnosis of an acute NXP2+ JDM with severe muscle involvement (muscle biopsy severity score: 20/27, VAS: 7/10), an indolent, slowly progressive MSA-negative JDM (muscle biopsy severity score: 13/27, VAS: 4/10), and on one healthy muscle (HM). ..

Article Title: Muscle Spatial Transcriptomic Reveals Heterogeneous Profiles in Juvenile Dermatomyositis and Persistence of Abnormal Signature After Remission.
Article Snippet: .. To define the transcriptomic signature of the different areas of affected muscle in JDM, we performed 10X Genomics Visium Spatial Gene Expression analysis on the muscle obtained at the diagnosis of an acute NXP2+ JDM with severe muscle involvement (muscle biopsy severity score: 20/27, VAS: 7/10), an indolent, slowly progressive MSA-negative JDM (muscle biopsy severity score: 13/27, VAS: 4/10), and healthy muscle (HM). ..

Staining:

Article Title: Spatial Single-cell Analysis Decodes Cortical Layer and Area Specification
Article Snippet: .. Visium Spatial Gene Expression Analysis (10x Genomics) was performed according to manufacturer’s user guide and demonstrated protocol (Visium CytAssist Spatial Gene Expression for Fresh Frozen – Methanol Fixation, H&E Staining, Imaging & Destaining, CG000614, Rev A; Visium CytAssist Spatial Gene Expression Reagent Kits User Guide, CG000495, Rev D). ..

Article Title: Spatial transcriptomics reveals human cortical layer and area specification.
Article Snippet: Visium spatial transcriptomic analysis Visium spatial gene expression analysis (10x Genomics) was performed according to the manufacturer’s user guide and demonstrated protocol (‘Visium CytAssist Spatial Gene Expression for Fresh Frozen–Methanol Fixation, H&E Staining, Imaging & Destaining, CG000614, Rev A; Visium CytAssist Spatial Gene Expression Reagent Kits User Guide, CG000495, Rev D’). .. Visium spatial transcriptomic analysis Visium spatial gene expression analysis (10x Genomics) was performed according to the manufacturer’s user guide and demonstrated protocol (‘Visium CytAssist Spatial Gene Expression for Fresh Frozen–Methanol Fixation, H&E Staining, Imaging & Destaining, CG000614, Rev A; Visium CytAssist Spatial Gene Expression Reagent Kits User Guide, CG000495, Rev D’). ..

Imaging:

Article Title: Spatial Single-cell Analysis Decodes Cortical Layer and Area Specification
Article Snippet: .. Visium Spatial Gene Expression Analysis (10x Genomics) was performed according to manufacturer’s user guide and demonstrated protocol (Visium CytAssist Spatial Gene Expression for Fresh Frozen – Methanol Fixation, H&E Staining, Imaging & Destaining, CG000614, Rev A; Visium CytAssist Spatial Gene Expression Reagent Kits User Guide, CG000495, Rev D). ..

Article Title: Spatial transcriptomics reveals human cortical layer and area specification.
Article Snippet: Visium spatial transcriptomic analysis Visium spatial gene expression analysis (10x Genomics) was performed according to the manufacturer’s user guide and demonstrated protocol (‘Visium CytAssist Spatial Gene Expression for Fresh Frozen–Methanol Fixation, H&E Staining, Imaging & Destaining, CG000614, Rev A; Visium CytAssist Spatial Gene Expression Reagent Kits User Guide, CG000495, Rev D’). .. Visium spatial transcriptomic analysis Visium spatial gene expression analysis (10x Genomics) was performed according to the manufacturer’s user guide and demonstrated protocol (‘Visium CytAssist Spatial Gene Expression for Fresh Frozen–Methanol Fixation, H&E Staining, Imaging & Destaining, CG000614, Rev A; Visium CytAssist Spatial Gene Expression Reagent Kits User Guide, CG000495, Rev D’). ..

Variant Assay:

Article Title: Spatial transcriptomics of a giant pilomatricoma.
Article Snippet: .. Giant PMs are a rare World Health Organization (WHO)-acknowledged PM variant that is greater than 4 cm in size, frequently ulcerate and are more likely to simulate a malignant neoplasm on clinical exam.4 Most PMs harbor mutations in the CTNNB1 gene5 leading to constitutive beta-catenin/lymphoid enhancer binding factor (LEF) target gene activation to control proliferation, differentiation, and survival.6,7 Simultaneous gain of chromosome 18 harboring the BCL2 apoptosis regulator (BCL2) gene is also a recurrent abnormality accompanied by BCL2 protein overexpression.8,9 Finally, one study has shown a positive correlation between yes-associated protein (YAP) expression and PM size.10 Spatial gene expression analyses allow for the measurement of gene expression while retaining spatial information, enabling visualization and statistical comparisons of gene expression differences across tissue regions.11,12 Here, we report 10X Genomics Visium Spatial Gene Expression analysis of a giant PM. ..

Binding Assay:

Article Title: Spatial transcriptomics of a giant pilomatricoma.
Article Snippet: .. Giant PMs are a rare World Health Organization (WHO)-acknowledged PM variant that is greater than 4 cm in size, frequently ulcerate and are more likely to simulate a malignant neoplasm on clinical exam.4 Most PMs harbor mutations in the CTNNB1 gene5 leading to constitutive beta-catenin/lymphoid enhancer binding factor (LEF) target gene activation to control proliferation, differentiation, and survival.6,7 Simultaneous gain of chromosome 18 harboring the BCL2 apoptosis regulator (BCL2) gene is also a recurrent abnormality accompanied by BCL2 protein overexpression.8,9 Finally, one study has shown a positive correlation between yes-associated protein (YAP) expression and PM size.10 Spatial gene expression analyses allow for the measurement of gene expression while retaining spatial information, enabling visualization and statistical comparisons of gene expression differences across tissue regions.11,12 Here, we report 10X Genomics Visium Spatial Gene Expression analysis of a giant PM. ..

Activation Assay:

Article Title: Spatial transcriptomics of a giant pilomatricoma.
Article Snippet: .. Giant PMs are a rare World Health Organization (WHO)-acknowledged PM variant that is greater than 4 cm in size, frequently ulcerate and are more likely to simulate a malignant neoplasm on clinical exam.4 Most PMs harbor mutations in the CTNNB1 gene5 leading to constitutive beta-catenin/lymphoid enhancer binding factor (LEF) target gene activation to control proliferation, differentiation, and survival.6,7 Simultaneous gain of chromosome 18 harboring the BCL2 apoptosis regulator (BCL2) gene is also a recurrent abnormality accompanied by BCL2 protein overexpression.8,9 Finally, one study has shown a positive correlation between yes-associated protein (YAP) expression and PM size.10 Spatial gene expression analyses allow for the measurement of gene expression while retaining spatial information, enabling visualization and statistical comparisons of gene expression differences across tissue regions.11,12 Here, we report 10X Genomics Visium Spatial Gene Expression analysis of a giant PM. ..

Control:

Article Title: Spatial transcriptomics of a giant pilomatricoma.
Article Snippet: .. Giant PMs are a rare World Health Organization (WHO)-acknowledged PM variant that is greater than 4 cm in size, frequently ulcerate and are more likely to simulate a malignant neoplasm on clinical exam.4 Most PMs harbor mutations in the CTNNB1 gene5 leading to constitutive beta-catenin/lymphoid enhancer binding factor (LEF) target gene activation to control proliferation, differentiation, and survival.6,7 Simultaneous gain of chromosome 18 harboring the BCL2 apoptosis regulator (BCL2) gene is also a recurrent abnormality accompanied by BCL2 protein overexpression.8,9 Finally, one study has shown a positive correlation between yes-associated protein (YAP) expression and PM size.10 Spatial gene expression analyses allow for the measurement of gene expression while retaining spatial information, enabling visualization and statistical comparisons of gene expression differences across tissue regions.11,12 Here, we report 10X Genomics Visium Spatial Gene Expression analysis of a giant PM. ..

Over Expression:

Article Title: Spatial transcriptomics of a giant pilomatricoma.
Article Snippet: .. Giant PMs are a rare World Health Organization (WHO)-acknowledged PM variant that is greater than 4 cm in size, frequently ulcerate and are more likely to simulate a malignant neoplasm on clinical exam.4 Most PMs harbor mutations in the CTNNB1 gene5 leading to constitutive beta-catenin/lymphoid enhancer binding factor (LEF) target gene activation to control proliferation, differentiation, and survival.6,7 Simultaneous gain of chromosome 18 harboring the BCL2 apoptosis regulator (BCL2) gene is also a recurrent abnormality accompanied by BCL2 protein overexpression.8,9 Finally, one study has shown a positive correlation between yes-associated protein (YAP) expression and PM size.10 Spatial gene expression analyses allow for the measurement of gene expression while retaining spatial information, enabling visualization and statistical comparisons of gene expression differences across tissue regions.11,12 Here, we report 10X Genomics Visium Spatial Gene Expression analysis of a giant PM. ..

Expressing:

Article Title: Spatial transcriptomics of a giant pilomatricoma.
Article Snippet: .. Giant PMs are a rare World Health Organization (WHO)-acknowledged PM variant that is greater than 4 cm in size, frequently ulcerate and are more likely to simulate a malignant neoplasm on clinical exam.4 Most PMs harbor mutations in the CTNNB1 gene5 leading to constitutive beta-catenin/lymphoid enhancer binding factor (LEF) target gene activation to control proliferation, differentiation, and survival.6,7 Simultaneous gain of chromosome 18 harboring the BCL2 apoptosis regulator (BCL2) gene is also a recurrent abnormality accompanied by BCL2 protein overexpression.8,9 Finally, one study has shown a positive correlation between yes-associated protein (YAP) expression and PM size.10 Spatial gene expression analyses allow for the measurement of gene expression while retaining spatial information, enabling visualization and statistical comparisons of gene expression differences across tissue regions.11,12 Here, we report 10X Genomics Visium Spatial Gene Expression analysis of a giant PM. ..

other:

Article Title: Astrocyte heterogeneity reveals region-specific astrogenesis in the white matter.
Article Snippet: Image acquisition, processing, quantification and statistical analysis Confocal microscopy was performed with a ZEISS LSM 710 microscope using the ZEN software (black edition, v.2.3 SP1, ZEISS) and a Leica TCS SP8 X microscope using the LAS X software (v.3.5.7.23225, Leica).

Biomarker Discovery:

Article Title: Muscle spatial transcriptomic reveals heterogeneous profiles in untreated juvenile dermatomyositis and the persistence of pathological signature after remission
Article Snippet: .. To define the transcriptomic signature of the different areas of affected muscle in JDM, we performed 10X Genomics Visium Spatial Gene Expression analysis on the muscle obtained at diagnosis of an acute NXP2+ JDM with severe muscle involvement (muscle biopsy severity score: 20/27, VAS: 7/10), an indolent, slowly progressive MSA-negative JDM (muscle biopsy severity score: 13/27, VAS: 4/10), and on one healthy muscle (HM). ..

Article Title: Muscle Spatial Transcriptomic Reveals Heterogeneous Profiles in Juvenile Dermatomyositis and Persistence of Abnormal Signature After Remission.
Article Snippet: .. To define the transcriptomic signature of the different areas of affected muscle in JDM, we performed 10X Genomics Visium Spatial Gene Expression analysis on the muscle obtained at the diagnosis of an acute NXP2+ JDM with severe muscle involvement (muscle biopsy severity score: 20/27, VAS: 7/10), an indolent, slowly progressive MSA-negative JDM (muscle biopsy severity score: 13/27, VAS: 4/10), and healthy muscle (HM). ..



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